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【公司名稱】廣州健侖生物科技有限公司

【市場(chǎng)部】楊永漢
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【騰訊】
【公司地址】廣州市清華科技園健新基地番禺石樓鎮(zhèn)健啟路63號(hào)二期2幢101-103室

The indirect immunofluorescence assay (IFA) uses whole-worms as antigens, and fluorescently labeled secondary antibodies detect specific antibodies. This method can be used to measure isotype and subtype antibodies, of which IgM is applicable and early clinical diagnosis. 4. Enzyme-linked immunosorbent assays (ELISAs) are used to detect host-specific circulating antibodies or antigens, and a variety of improved methods have been widely used for the early diagnosis of acute infections and congenital toxoplasmosis. PCR and DNA probe technology are now used to detect Toxoplasma gondii infection, which is more sensitive, specific and early diagnostic. At present, it has also begun to be used in clinical trials. It is limited to laboratory conditions and cannot be applied in the country. The disease is an animal-borne disease and it is distributed in all regions of the world on five continents. Many mammals (about 14 species) and birds are important sources of infection for this disease. Population infection is also quite common. According to serological surveys, the population antibody positive rate was 25% to 50%. In China, it is 5% to 20%, and most of them are latent infections. In domestic cases of Toxoplasma gondii in humans, since Tse Tianhua (1962) reported a clinical case of congenital cerebral hypoplasia and chorioretinitis in Jiangxi province, there have been ten cases of Toxoplasma gondii isolates. The positive rate of livestock can reach 10% to 50%, and it often forms a local outbreak, which seriously affects the development of animal husbandry and also threatens human health. Causes of widespread epidemics: 1 Many kinds of life history are infectious; 2 intermediate hosts are wide, livestock and poultry are all susceptible; 3 can be multi-directionally spread between terminal host and intermediate host, intermediate host and intermediate host. 4 cysts can survive in the intermediate host tissues for a long period of time; 5 the oocysts have large emissions and strong external environmental resilience. Popular links (1) Source of infection: Animals are the main source of infection, while cats and felines are important sources of infection. The vertical transmission of humans through the placenta has the significance of the source of infection. (2) Routes of transmission: There are both congenital and acquired. The former refers to the infection of the fetus through the placenta of the mother's blood; the latter is mainly caused by oral infections, which can be eaten by ingestion of uncooked meat products, eggs, and milk containing toxoplasma. There have been reports of acute infections caused by drinking raw goat milk. Damaged skin and mucous membranes are also a route of infection and laboratory personnel must pay attention. In addition, contact with soil and water contaminated by oocysts is also an important route. There have been reports of transfusion and toxoplasmosis in foreign countries. Arthropods carry oocysts also have a certain significance. (3) Susceptible population: Humans are generally susceptible to Toxoplasma gondii, especially fetuses, infants, children with tumors, and AIDS patients. Long-term use of immunosuppressants and immunocompromised patients can cause recurrent symptoms of latent infection. Occupation, lifestyle and eating habits are closely related to the rate of Toxoplasma gondii infection.

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